drospirenone will boost the level or outcome of salmeterol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unidentified.fedratinib will raise the degree or outcome of salmeterol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Change dose of medications that are CYP3A4 substra

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